An experimental drug that held great promise in driving down a dangerous form of cholesterol didn’t show any measurable impact on heart attack or stroke in a clinical trial. The failure of the Novartis drug pelacarsen to help people who have high levels of lipoprotein(a) stunned researchers, who...
safety
Three people were killed and one other person was injured when a CHP chase ended in a crash in Baldwin Park, authorities said.
safety
Five people were killed and more than a dozen injured after a gunman opened fire in a busy market square in Krakow, Poland, police said.
safety
A tragic skydiving accident left two licensed skydivers dead after they collided midair in Southern California.
Local
The Vincent Thomas Bridge closed to traffic just after midnight Saturday and will remain shut for 16 months while Caltrans replaces the bridge deck in a $750 million project....
News
First lady Melania Trump will be in Louisiana Saturday night to announce a $5 million scholarship program for foster kids to attend Louisiana State University....
parks
President Donald Trump's new White House chief of staff, Stephen Miller, is behind many of the administration's signature domestic policy initiatives — especially its sweeping crackdown on immigration....
News
Russell Brand's convictions Thursday for rape and sexual assault have turned a spotlight back on the BBC and other media employers.
News
Child abuse allegations against foster mother Carprice Williams, who is charged with the murder of Malayshia Allford in Philadelphia, PA, are raising questions....
government
Mayor-elect Raman says she will cut homelessness in half by 2028, end it by 2030. Can she deliver?
schools
LAUSD's beloved coffee cake. (Photo collage by Elina Shatkin / LAist) Micki Boden wanted a wedding cake that checked off a couple of big boxes — personalized and tasty. Instead of a traditional tiered cake, the San Fernando Valley native went with a favorite from her school days....
News
Gelato sold in nine states and Washington, DC, has been recalled and upgraded to the highest risk level because of Listeria contamination.
