Novak Djokovic experienced a tough start at the US Open, losing in the opening round for the first time. He was defeated by Mariano Navone in a 5-set match. Djokovic struggled with physical and internal ailments during the match, compounding his difficulties with a series of mistakes.

Despite his efforts, Djokovic was unable to overcome these challenges and ultimately lost to Navone. The match was closely contested, going to 5 sets.

Further details about the match are available from the source, providing more insight into Djokovic's performance and the outcome of the match.